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KMID : 0359319780180020077
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Korean Journal of Veterinary Research
1978 Volume.18 No. 2 p.77 ~ p.86
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Studies on the Variation of Nonprotein Nitrogen Compounds in the Blood of Rabbits Administered with Panax ginseng
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Abstract
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The present study was carried out to evaluate the effect of panax ginseng on the metabolism of nonprotein nitrogen compounds in rabbit blood. After rabbits were administered with ginseng powder orally for 30 days or with ginseng extract intraperiteneally for 10 days, the blood was collected from portal and ear vein to measure ammonia, urea, creatinine and nonprotein nitrogen.
The blood ammonia level in ear vein of control rabbits was 87.0±5.1㎍/100㎖ and was not significantly different from that of rabbits which were administered with ginseng powder orally or with ginseng extract intraperitoneally. But oral administration of ginseng powder produced a great decrease in ammonia level of portal vein from 1,392 to 704 ㎍ per 100㎖, suggesting that intestinal ammonia production is suppressed by ginseng powder due to its antimicrobial activity. While there was no significant difference between the control and the rabbits which were administered with ginseng extract intraperitoneally.
Ginseng administration had no effect on the creatinine level in blood from ear and portal vein, except the intraperitoneal injection of ginseng extract. It slightly lowered the creatinine level only in ear vein blood. The values of urea and nonprotein nitrogen were net affected by the administration of ginseng.
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